[That gets some of the tension to leave him and his gaze darts for a moment before he corrects it.]

I know you're not trying to upset me. And I'm... I'm not upset at you, I'm more upset with the situation. I'm upset that you can't see yourself the way I do. You're different, yes, and you don't always process things the same way most people do, but I can never see that as "defective". You're a wonderful person, and I'm convinced you're a good person.

[He knows Wesker will never agree with that, but he needs to say it.]